CAS number：329317-98-8 molecular formula：C26H26F6N2O4S2
PTP抑制剂IV是一种不带电荷的1,4-二取代，苯基连接的双三氟甲基磺酰胺基（TFMS）磷酸酯模拟物，可作为有效的，可逆的，竞争性的和主动位点的蛋白质酪氨酸磷酸酶抑制剂。PTP抑制剂IV是PTPβ，PTPε，PTPμ，PTPσ，PTP-MEG，PTP1B和SH-PTP2的抑制剂。 PTP Inhibitor IV is an uncharged, 1,4-di-substituted, phenyl-linked bis-trifluoromethylsulfonamido (TFMS) phosphate mimetic which acts as a potent, reversible, competitive, and active-site directed inhibitor of protein tyrosine phosphatases. PTP Inhibitor IV is an inhibitor of PTP β, PTP ε, PTP μ, PTP σ, PTP-MEG, PTP1B and SH-PTP2.
| Chinese alias | - | ||
| English alias | 1,1,1-trifluoro-N-[4-[2-[4-[2-[4-(trifluoromethylsulfonylamino)phenyl]propan-2-yl]phenyl]propan-2-yl]phenyl]methanesulfonamide | Protein Tyrosine Phosphatase Inhibitor IV | ||
| CAS number | 329317-98-8 | molecular formula | C26H26F6N2O4S2 |
| molecular weight | 608.61 g/mol | Exact mass | ≥98% |
| PSA | 109.000 Ų | logp | 7.9 |
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