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4-[(1-oxo-7-phenylheptyl)amino]-(4R)-octanoic acid

CAS number:1101136-50-8    molecular formula:C21H33NO3

overview

compound introduction

4-[(1-氧代-7-苯基庚基)氨基]-(4R)-辛酸是一种基于(R)-α-正亮氨酸的简单酰胺,是sPLA2的选择性抑制剂。它对0.091摩尔分数的sPLA2表现出95%的抑制作用(XI(50)= 0.003),而不会影响cPLA2或iPLA2的活性。 4-[(1-oxo-7-phenylheptyl)amino]-(4R)-octanoic acid a simple amide based on (R)-α-norleucine, is a selective and potent inhibitor of sPLA2. It exhibits 95% inhibition (XI(50) = 0.003) of sPLA2 at 0.091 mole fraction without affecting the activities of cPLA2 or iPLA2.

Specs

Chinese alias-
English alias(4R)-4-[(7-Phenylheptanoyl)amino]octanoic acid
CAS number1101136-50-8molecular formulaC21H33NO3
molecular weight347.5 g/molExact mass-
PSA66.400 Ųlogp5.1

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