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Aloesin

CAS number:30861-27-9    molecular formula:C19H22O9

overview

compound introduction

Aloesin (Aloeresin) 是芦荟的一种活性成分,具有抗炎、紫外线保护和抗菌作用。Aloesin通过 MAPK 信号通路发挥抗癌作用。 芦荟苦素是一种C-糖基化的色酮化合物,已显示出酪氨酸酶的竞争性抑制活性,酪氨酸酶是一种负责催化植物中苯酚氧化的酶。已经观察到芦荟苦素的衍生物表现出自由基清除和抗炎活性,并且还已经报道了该化合物调节黑色素的形成(黑色素生成)。 Aloesin is a C-glycosylated chromone compound that has shown competitive inhibitory activity of tyrosinase, an enzyme responsible for catalyzing phenol oxidation in plants. Derivatives of aloesin have been observed to exhibit free radical scavenging and anti-inflammatory activity, and this compound has also been reported to modulate the formation of melanin (melanogenesis).

Specs

Chinese alias-
English alias2-acetonyl-7-hydroxy-5-methyl-8-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]chromen-4-one | SCHEMBL6936841 | ALOESIN [MI] | AC-34460 | 8-beta-D-glucopyranosyl-7-hydroxy-5-methyl-2-(2-oxopropyl)-4H-1-benzopyran-4-one | C08994 |
CAS number30861-27-9molecular formulaC19H22O9
molecular weight394.37 g/molExact mass10mM in DMSO
PSA154.000 Ųlogp-1.300

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