PF-9366 是一种有效的甲硫氨酸腺苷转移酶 (Mat2A) 抑制剂,IC50 值和 Kd 值分别为 420 nM 和 170 nM。 Information PF-9366 PF-9366 is a human methionine adenosyltransferase 2A (Mat2A) inhibitor with IC50 of 420 nM and Kd of 170 nM. Targets hMat2A (Cell-free assay); hMat2A (Cell-free assay) 170 nM(Kd); 420 nM
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PF-9366
CAS number:72882-78-1 molecular formula:C2OH19ClN4
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compound introduction
Specs
| Chinese alias | - | ||
| English alias | 7-Chloro-N,N-dimethyl-5-phenyl-[1,2,4]triazolo[4,3-a]quinoline-1-ethanamine | ||
| CAS number | 72882-78-1 | molecular formula | C2OH19ClN4 |
| molecular weight | 350.84 g/mol | Exact mass | ≥97% |
| PSA | 33.400 Ų | logp | 4.355 |
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