Information ZK824859 ZK824859 is a potent, selective and orally bioavailable inhibitor of urokinase plasminogen activator (uPA) with IC50 of 79 nM, 1580 nM and 1330 nM for human uPA, tPA, and plasmin, respectively. Targets human uPA (Cell-free assay); human plasmin (Cell-free assay); human tPA (Cell-free assay) 79 nM; 1330 nM; 1580 nM
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ZK824859
CAS number:2254001-81-3 molecular formula:C22H20F2N2O4
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| Chinese alias | - | ||
| English alias | Butanoic acid,2-[[6-[[3'-(aminomethyl)[1,1'-biphenyl]-3-yl]oxy]-3,5-difluoro-2-pyridinyl]oxy]-,(2R)- | ||
| CAS number | 2254001-81-3 | molecular formula | C22H20F2N2O4 |
| molecular weight | 414.4 g/mol | Exact mass | ≥99% |
| PSA | 94.700 Ų | logp | 2.3 |
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