CAS number：874590-32-6 molecular formula：C17H17N3O2S
M1001 是一种较弱的 HIF-2α 激动剂，直接与 HIF-2α PAS-B 结构域结合，Kd 值为 667 nM。M1001 能够增强 HIF-2α-ARNT 复合体之间的稳定性。 Information M1001 M1001 is a weak agonist of hypoxia-inducible factor-2α (HIF-2α) that binds to the HIF-2α PAS-B domain with Kd of 667 nM. Targets HIF-2α PAS-B domain (Cell-free assay) 667 nM(Kd)
| Chinese alias | - | ||
| English alias | 1,2-Benzisothiazol-3-amine,N-[2-(1-pyrrolidinyl)phenyl]-,1,1-dioxide | ||
| CAS number | 874590-32-6 | molecular formula | C17H17N3O2S |
| molecular weight | 327.4 g/mol | Exact mass | 10mM in DMSO |
| PSA | 70.200 Ų | logp | 2.173 |
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