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FB23

CAS number:2243736-35-6    molecular formula:C18H14Cl2N2O3

overview

compound introduction

Information FB23 FB23 is a potent and selective inhibitor of FTO demethylase with IC50 of 60 nM. FB23 directly binds to FTO and selectively inhibits FTO's mRNA N6-methyladenosine (m6A) demethylase activity. Targets FTO demethylase (Cell-free assay) 60 nM

Specs

Chinese alias-
English aliasBenzoic acid,2-​[[2,​6-​dichloro-​4-​(3,​5-​dimethyl-​4-​isoxazolyl)​phenyl]​amino]​-
CAS number2243736-35-6molecular formulaC18H14Cl2N2O3
molecular weight377.22 g/molExact mass10mM in DMSO
PSA75.400 Ųlogp5.7

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