CAS number：1399177-37-7 molecular formula：C27H29N5O
Denifanstat (TVB-2640) 是一种口服有效的选择性 FASN 抑制剂，IC50 为 0.052 μM，EC50 为 0.072 μM。Denifanstat 有潜力用于脂肪肝和癌症研究 应用： TVB-2640 (ASC-40, FASN-IN-2) 是一种口服生物可利用的 fatty acid synthase (FAS/FASN) 的抑制剂，对NAFLD和非酒精性脂肪性肝炎具有治疗潜力。 Information TVB-2640 TVB-2640 (ASC-40, FASN-IN-2) is an orally bioavailable, pharmacological fatty acid synthase (FAS/FASN) inhibitor with therapeutic potential in patients with NAFLD and nonalcoholic steatohepatitis. Targets FAS
| Chinese alias | - | ||
| English alias | Denifanstat | 4-[1-[4-cyclobutyl-2-methyl-5-(5-methyl-1H-1,2,4-triazol-3-yl)benzoyl]piperidin-4-yl]benzonitrile | 1399177-37-7 | FT-0654318 | A937502 | 4GF95B2LZA | Denifanstat [INN] | 3-(t-butoxycarbonylamino)propanoic acid | BDBM137084 | UNII-4GF95B2LZA | ||
| CAS number | 1399177-37-7 | molecular formula | C27H29N5O |
| molecular weight | 439.55 g/mol | Exact mass | 10mM in DMSO |
| PSA | 85.700 Ų | logp | 4.638 |
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