compound introduction
产品介绍 Epoxomicin (BU-4061T) 是一种含环氧酮的天然产物，是一种有效的，选择性的和不可逆的蛋白酶体 (proteasome) 抑制剂。Epoxomicin 与蛋白酶体的LMP7，X，MECL1 和 Z 催化亚基共价结合，并有效地主要抑制类胰凝乳蛋白酶的活性。Epoxomicin 可以穿越血脑屏障，并具有很强的抗肿瘤和抗炎活性。
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Epoxomicin
CAS number：134381-21-8 molecular formula：C28H50N4O7
overview
Specs
| Chinese alias | 环氧酶素 | N-乙酰基-N-甲基-L-异亮氨酰基-L-异亮氨酰基-N-[((1S)-3-甲基-1-[[((2R)-2-甲基环氧乙烷基]羰基]丁基]-L-苏氨酸酰胺' | ||
| English alias | N-acetyl-N-methyl-L-isoleucyl-L-isoleucyl-N-((1S)-3-methyl-1-(((2R)-2-methyl-2-oxiranyl)carbonyl)butyl)-L-threoninamide | N-Acetyl-N-methyl-L-isoleucyl-L-isoleucyl-N-(3-methyl-1-((2-methyloxiranyl)carbonyl)butyl)-L-threoninamide | 3-Bromo-2-hydroxypyridin | ||
| CAS number | 134381-21-8 | molecular formula | C28H50N4O7 |
| molecular weight | 554.73 g/mol | Exact mass | ≥97% |
| PSA | 157.000 Ų | logp | 2.300 |
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