CAS number：1919853-46-5 molecular formula：C34H36N2O9S2
Information PTP1B-IN-2 PTP1B-IN-2 (MDK3465, Ptp1B-In-2, Compound P6) is a potent and selective protein tyrosine phosphatase-1B (PTP1B) inhibitor with IC50 of 50 nM. PTP1B-IN-2 enhances insulin-mediated insulin receptor β (IRβ) phosphorylation and insulin-stimulated glucose uptake. Targets PTP1B (Cell-free assay) 50 nM
| Chinese alias | - | ||
| English alias | MDK3465 | Ptp1B-In-2 | Compound P6Benzoic acid,5-[[[4-[(2-methoxy-2-oxoethyl)(methylsulfonyl)amino]phenyl]methyl][(phenylmethyl)sulfonyl]amino]-2-[(4-methylphenyl)methoxy]-,methyl ester | ||
| CAS number | 1919853-46-5 | molecular formula | C34H36N2O9S2 |
| molecular weight | 680.79 g/mol | Exact mass | ≥99% |
| PSA | 153.000 Ų | logp | 4.846 |
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