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SR 0987

CAS number:303126-97-8    molecular formula:C16H10ClF6NO2

overview

compound introduction

SR0987是SR1078 的一个类似物,是 RORγt 的一个激动剂,其 EC50 值为800 nM。SR0987 可上调IL17 的表达且抑制PD-1 的表达。 SR0987, a SR1078 analog, is a RORγt agonist, with an EC50 of 800 nM. SR0987 increases IL17 expression while repressing the expression of PD-1。

Specs

Chinese alias2-氯-N-[4-[2,2,2-三氟-1-羟基-1-(三氟甲基)乙基]苯基]苯甲酰胺 | 2-氯-N-(4-(1,1,1,3,3,3-六氟-2-羟基-2-丙烷基)苯基)苯甲酰胺
English alias2-Chloro-N-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]benzamide | 2-Chloro-N-(4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl)benzamide
CAS number303126-97-8molecular formulaC16H10ClF6NO2
molecular weight397.7 g/molExact mass≥98%(HPLC)
PSA49.300 Ųlogp4.600

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