CAS number：489415-96-5 molecular formula：C31H33N3O5
Information SBC-115076 SBC-115076 is a potent extracellular proprotein convertase subtilisin kexin type 9 ( PCSK9 ) antagonist. Targets PCSK9 In vitro In HepG2 cells, SBC-115076 increases the uptake of Fluorescent Dil-LDL. In vivo In mice that are fed high fat diet, SBC-115076 (8 mg/kg) lowers cholesterol levels by 32%.
| Chinese alias | - | ||
| English alias | 4-(4-(benzyloxy)-3-methylbenzoyl)-3-hydroxy-1-(3-morpholinopropyl)-5-(pyridin-4-yl)-1H-pyrrol-2(5H)-one | ||
| CAS number | 489415-96-5 | molecular formula | C31H33N3O5 |
| molecular weight | 527.61 g/mol | Exact mass | ≥98% |
| PSA | 92.200 Ų | logp | 3.700 |
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