Lidorestat (IDD-676) 是一种有效的,选择性的, 醛糖还原酶 (aldose reductase) 抑制剂,IC50 为 5 nM。Lidorestat 可用于慢性糖尿病并发症的治疗。Lidorestat 还可改善神经传导并减少白内障形成。 Lidorestat (IDD-676) is a potent, selective aldose reductase inhibitor with an IC50 of 5 nM. Lidorestat can be used for chronic diabetes complications. Lidorestat also improves nerve conduction and reduces cataract formation
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Lidorestat (IDD-676)
CAS number:245116-90-9 molecular formula:C18H11F3N2O2S
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| Chinese alias | 利多司他 | ||
| English alias | 2-(3-((4,5,7-trifluorobenzo[d]thiazol-2-yl)methyl)-1H-indol-1-yl)acetic acid | Lidorestat anhydrous | IDD 676 | R3734K0M7L | IDD-676 | Lidorestat | IDD-000676-01 | ||
| CAS number | 245116-90-9 | molecular formula | C18H11F3N2O2S |
| molecular weight | 376.35 g/mol | Exact mass | - |
| PSA | 83.400 Ų | logp | 4.4 |
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