CAS number：1673571-51-1 molecular formula：C29H31ClF3N5O3
Rodatristat ethyl (KAR5585) 是一种首创的 tryptophan hydroxylase 1 (TPH1) 抑制剂，具有体外纳摩尔浓度，可降低 5-hydroxytryptamine (5-HT) 的水平并显着降低肺动脉高压 (PAH)， Rodatristat ethyl (KAR5585) is a first-in-class tryptophan hydroxylase 1 (TPH1) Inhibitor with nanomolar in vitro potency. Rodatristat ethyl reduces the level of 5-HT and significantly reduces pulmonary arterial hypertension (PAH).
| Chinese alias | 罗达司他乙酯 | ||
| English alias | Rodatristat ethyl | KAR5585 | Rodatristat ethyl [USAN] | 507FY6OL37 | 2,8-Diazaspiro(4.5)decane-3-carboxylic acid | RVT-1201 | ||
| CAS number | 1673571-51-1 | molecular formula | C29H31ClF3N5O3 |
| molecular weight | 590.04 g/mol | Exact mass | - |
| PSA | 103.000 Ų | logp | 6.1 |
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