compound introduction
Gcase activator 2 (compound 14), a pyrrolo[2,3-b]pyrazine, is alos a β-Glucocerebrosidase ( GCase ) activator ( EC 50 =3.8 μM). Gcase activator 2 induces GCase dimerizatio (both K-type and V-type). And Gcase activator 2 has low metabolic clearance in human and mouse In Vitro Gcase activator 2 has low metabolic clearance in human and mouse with CL values of 10 and 12 μL/min/mg, respectively. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid IC50& Target:β-Glucocerebrosidase
