ADDA 5 hydrochloride is a partial non-competitive inhibitor of cytochrome c oxidase (CcO) , with IC 50 s of 18.93 μM and 31.82 μM for purified CcO from human glioma and bovine heart, respectively. In Vitro ADDA 5 hydrochloride is a partial non-competitive inhibitor of CcO, with IC 50 s of 18.93 μM and 31.82 μM for purified CcO from human glioma and bovine heart, respectively. ADDA 5 inhibits CcO activity in UTMZ and Jx22-derived GSCs, with IC 50 s of 21.4 ± 3.9 μM and 15.5 ± 2.8 μM. ADDA 5 (25 μM) shows a growth inhibitory effect on UTMZ cells, with an EC 50 of 8.17 μM. MCE has not independently confirmed the accuracy of these methods. They are for reference only. In Vivo ADDA 5 (8 mg/kg, i.p.) significantly suppresses the growth of tumor in mice. ADDA 5 does not causes detectable toxicity at up to 80 mg/kg in mice . MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid IC50& Target:IC50: 18.93 μM (CcO, human glioma), 31.82 μM (CcO, bovine heart)
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ADDA 5 hydrochloride
CAS number：473268-46-1 molecular formula：C24H36ClNO2
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| Chinese alias | ADDA 5 盐酸盐 | ||
| English alias | - | ||
| CAS number | 473268-46-1 | molecular formula | C24H36ClNO2 |
| molecular weight | 406 g/mol | Exact mass | ≥98% |
| PSA | 32.700 Ų | logp | - |
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