(5E,9E,13E)-Teprenone ((5E,9E,13E)-Geranylgeranylacetone) is an isomer of Teprenone with antiulcer activity. (5E,9E,13E)-Teprenone induces transcriptional activation of HSP genes that may increase gastric mucosal defense at conditions of stress. In Vitro (5E,9E,13E)-Teprenone might transiently activate the transcription of HSP70 gene. The heat shock element–binding activity reflects the activation of heat shock factor 1 in response to (5E,9E,13E)-Teprenone. MCE has not independently confirmed the accuracy of these methods. They are for reference only. In Vivo (5E,9E,13E)-Teprenone induces hat sock proteins accumulations in rat gastric mucosa . MCE has not independently confirmed the accuracy of these methods. They are for reference only. Animal Model: Male Wister strain rats (≈250 g) Dosage: 200 mg/kg Administration: Oral administration Result: Caused accumulations of all of HSP90, HSP70, HSC70 and HSP60 within 60 minutes. Form:Liquid
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(5E,9E,13E)-Teprenone
CAS number：3796-63-2 molecular formula：C23H38O
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| Chinese alias | (5E,9E,13E)-替普瑞酮 | ||
| English alias | - | ||
| CAS number | 3796-63-2 | molecular formula | C23H38O |
| molecular weight | 330.55 g/mol | Exact mass | ≥99% |
| PSA | - | logp | - |
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