CAS number：1815613-42-3 molecular formula：C19H23F4N3O
BMS-986176 (LX-9211) 是一种有效的，高选择性、可穿过血脑屏障的 AAK1 (adaptor associated kinase 1) 抑制剂，IC50 为 2 nM。BMS-986176 可用于神经退行性疾病的研究。 BMS-986176 (LX-9211) is a highly selective, brain-penetrant, potent AAK1 (adaptor associated kinase 1) inhibitor with an IC50 of 2 nM. BMS-986176 can be used for neurodegenerative diseases research.
| Chinese alias | BMS986176 | LX-9211 | LX9211 | ||
| English alias | US10155760, Example 123 | BMS-986176 | 1815613-42-3 | 9G4RLM5X6Z | UNII-9G4RLM5X6Z | LX9211 | LX-9211 | AAK1-IN-1 | (2S)-1-((2',6-Bis(difluoromethyl)(2,4'-bipyridin)-5-yl)oxy)-2,4-dimethyl-2-pentanamine | ||
| CAS number | 1815613-42-3 | molecular formula | C19H23F4N3O |
| molecular weight | 385.40 g/mol | Exact mass | - |
| PSA | 61.000 Ų | logp | 3.7 |
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