compound introduction
Basmisanil (RG1662) 是一种高选择性含 α 亚基 GABAA 受体 (GABAAα5) 的负变构调节剂，具有口服活性。Basmisanil 可以抑制 GABAA-α5， Ki 值为 5 nM 和 IC50 值为 8 nM。Basmisanil 可用于多种认知和精神障碍的研究。
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Basmisanil
CAS number：1159600-41-5 molecular formula：C21H20FN3O5S
overview
Specs
| Chinese alias | example 112 [WO2009071476] | RG-1662 | RG1662 | ||
| English alias | DB11877 | EX-A1272 | (1,1-dioxo-1,4-thiazinan-4-yl)-[6-[[3-(4-fluorophenyl)-5-methyl-1,2-oxazol-4-yl]methoxy]pyridin-3-yl]methanone | (1,1-Dioxo-4-thiomorpholinyl)(6-((3-(4-fluorophenyl)-5-methylisoxazol-4-yl)methoxy)pyridin-3-yl)methanone | AC-35398 | Ba | ||
| CAS number | 1159600-41-5 | molecular formula | C21H20FN3O5S |
| molecular weight | 445.46 g/mol | Exact mass | - |
| PSA | 111.000 Ų | logp | 1.9 |
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