CAS number：252920-94-8 molecular formula：C23H23ClN2O3
Solabegron (GW 427353) 是一种β3肾上腺素能受体 (β3-AR)的选择性激动剂, 在中国仓鼠卵巢细胞中测得 EC50=22 nM，可用于研究膀胱过度活跃和肠易激综合征。 Solabegron (GW 427353) is a selective β3-adrenergic receptor agonist, stimulating cAMP accumulation in Chinese hamster ovary cells expressing the human β3-AR, with an EC50 value of 22 nM. Solabegron (GW 427353) is being developed for the treatment of overactive bladder and irritable bowel syndrome.
| Chinese alias | 索拉贝隆 | ||
| English alias | Solabegron | Solabegron (hydrochloride) | (R)-3'-((2-((2-(3-chlorophenyl)-2-hydroxyethyl)amino)ethyl)amino)-(1,1'-biphenyl)-3-carboxylic acid | AKOS016003955 | HY-19436 | (R)-3'-((2-((2-(3-Chlorophenyl)-2-hydroxyethyl)amino)ethyl)amino)-[1,1'-biphenyl]-3- | ||
| CAS number | 252920-94-8 | molecular formula | C23H23ClN2O3 |
| molecular weight | 410.89 g/mol | Exact mass | - |
| PSA | 81.600 Ų | logp | 1.8 |
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