SDZ 220-581 Ammonium salt is an orally active, potent, competitive NMDA receptor antagonist with pK i value of 7.7 In Vivo SDZ 220-581 (3.2-32 mg/kg; oral administration; for 24 hours; male OF-l mice) treatment dose-dependently protects mice against maximal electroshock seizures (MES). The time-course of protection by SDZ 220-581 is characterized by a rapid onset and long duration of action . MCE has not independently confirmed the accuracy of these methods. They are for reference only. Animal Model: Male OF-l mice (18-26 g) Dosage: 3.2 mg/kg, 10 mg/kg, 32 mg/kg Administration: Oral administration; for 24 hours Result: Dose-dependently protected mice against maximal electroshock seizures (MES) upon oral administration. Form:Solid IC50& Target:pKi: 7.7 ( NMDA receptor )
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SDZ 220-581 Ammonium salt
CAS number：179411-94-0 molecular formula：C16H20ClN2O5P
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| Chinese alias | SDZ 220-581 铵盐 | ||
| English alias | sdz-220581 | HY-13059A | SDZ 220-581 Ammonium salt | (2S)-2-amino-3-[3-(2-chlorophenyl)-5-(phosphonomethyl)phenyl]propanoic acid;azane | AKOS040737812 | SDZ 220-581 (Ammonium salt) | ||
| CAS number | 179411-94-0 | molecular formula | C16H20ClN2O5P |
| molecular weight | 386.77 g/mol | Exact mass | - |
| PSA | 122.000 Ų | logp | - |
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