compound introduction
(R)-ADX-47273 is a potent mGluR5 positive allosteric modulator, with an EC 50 of 168 nM for potentiation . In Vitro (R)-ADX-47273 (ADX-47273 (5)) is a potent mGluR5 positive allosteric modulator with an EC 50 for potentiation of 168 nM and a 9-fold shift of the glutamate response curve at 1 μM. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid IC50& Target:mGlu 5 168 nM (EC 50 )
