Bis-PEG4-acid 是一种 PROTAC linker,属于 PEG 类。可用于合成 PROTAC 分子。 Bis-PEG4-acid is a PEG derivative containing two terminal carboxylic acid groups. The hydrophilic PEG spacer increases solubility in aqueous media. The terminal carboxylic acids can be reacted with primary amine groups in the presence of activators (e.g. EDC, or DCC) to form a stable amide bond.
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Bis-PEG4-acid
CAS number:31127-85-2 molecular formula:C12H22O8
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Specs
| Chinese alias | 4,7,10,13-四氧杂十六烷-1,16-二酸 | ||
| English alias | 4,7,10,13-Tetraoxahexadecane-1,16-dioic acid | ||
| CAS number | 31127-85-2 | molecular formula | C12H22O8 |
| molecular weight | 294.30 g/mol | Exact mass | ≥98% |
| PSA | 112.000 Ų | logp | -1.4 |
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