L-NG-Monomethylarginine, Acetate Salt (L-NMMA), is an analogue of L-arginine that has been shown to inhibit Ca2+-dependent NOS3 (endothelial NOS) from porcine aorta. In an experiment on porcine aortic rings, L-NMMA was shown to cause contraction and inhibition of the endothelium-dependent relaxation induced by acetylcholine. This compound has also been noted to elicit a dose-dependent increase in mean systemic arterial blood pressure accompanied by bradycardia. Experiments on cat vascular endothelia show that L-NMMA can increase leukocyte adherence and emigration and reduce venular shear rate. Low shear rates have been shown to promote platelet-endothelial and leukocyte-endothelial cell adhesion in mesenteric venules. L-NG-Monomethylarginine, Acetate Salt (L-NMMA) is an inhibitor of NOS1 and NOS2. An L-arginine analogue inhibitor of Ca2+-dependent NOS3 (endothelial NOS)
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NG-Monomethyl-L-arginine Acetate
Dangerous GoodsCAS number：53308-83-1 molecular formula：C7H16N4O2·C2H4O2
overview
compound introduction
Specs
| Chinese alias | NG-甲基-L-精氨酸 乙酸盐 | Nω-甲基-L-精氨酸 乙酸盐 | NG-一甲基-L-精氨酸 乙酸盐 | N5-(甲基脒基)-L-鸟氨酸 乙酸盐 | L-NMMA 一乙酸酯 | N5-[亚氨基(甲基氨基)甲基]-L-鸟氨酸单乙酸盐 | ||
| English alias | (E)-Nw'-methyl-L-arginine compound with acetic acid (1:1) | CCG-222054 | HMS2235N20 | HMS3262E22 | Q27254685 | NG-MONOMETHYL-L-ARGININEACETATE | CAS-53308-83-1 | NCGC00024780-01 | D09018 | NCGC00094091-01 | SCHEMBL1321022 | SMR000857170 | N(G)-Methyl-L-ar | ||
| CAS number | 53308-83-1 | molecular formula | C7H16N4O2·C2H4O2 |
| molecular weight | 248.28 g/mol | Exact mass | - |
| PSA | 151.000 Ų | logp | - |
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Safety information
WGK Germany：
3
Personal protective equipment：
Eyeshields， Gloves， type N95 (US)， type P1 (EN143) respirator filter
RTECS：
RM2982000
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