compound introduction
ExatecanIntermediate 5 是Exatecan 的中间体。Exatecan (DX-8951) 是一种 DNA 拓扑异构酶 I (topoisomeraseI) 抑制剂，IC50 值为 2.2 μM (0.975 μg/mL)，可用于癌症研究。Exatecan Intermediate 5 可用于合成抗体-药物偶联物 (Antibody-Drug Conjugates (ADCs))。
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N,N'-(3-Fluoro-4-methyl-8-oxo-5,6,7,8-tetrahydronaphthalene-1,7-diyl)diacetamide
CAS number：143655-70-3 molecular formula：
overview
Specs
| Chinese alias | - | ||
| English alias | - | ||
| CAS number | 143655-70-3 | molecular formula | |
| molecular weight | 292.300 g/mol | Exact mass | ≥99% |
| PSA | 75.300 Ų | logp | 1.7 |
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