CAS number：1493764-08-1 molecular formula：C25H33N7O2
UNC2881 是一种特异性的Mer tyrosine kinase抑制剂，IC50为 4.3 nM, 其选择性分别超过Axl和Tyro3的选择性 83倍，58倍。 Biochemical mechanism: UNC2881 is a selective inhbitor of Mer kinase, a member of the TAM (Tyro3, Axl, Mer) receptor tyrosine kinase family. The IC50 values for inhibition of Mer, Axl and Tyro 3 are 4.3, 360 and 250 nM, respectively.
| Chinese alias | 2-(丁基氨基)-4-[(反式-4-羟基环己基)氨基] -N-[[4-(1H-咪唑-1-基)苯基]甲基] -5-嘧啶甲酰胺 | ||
| English alias | - | ||
| CAS number | 1493764-08-1 | molecular formula | C25H33N7O2 |
| molecular weight | 463.58 g/mol | Exact mass | 10mM in DMSO |
| PSA | 117.000 Ų | logp | 3.800 |
No numbering system information yet
No physical and chemical property information yet
No safety information yet
No production method and use information yet
No upstream information yet
No downstream information yet
