GRL0617 是一种选择性的,竞争性非共价的 severe acute respiratory syndrome (SARS-CoV) papain-like protease (PLpro) 抑制剂,其 IC50 值为 0.6 μM,Ki 值为 0.49 μM。GRL0617 对 SARS-CoV 具有抑制作用,其 EC50 值为 14.5 μM。GRL0617 可用于急性呼吸综合征的研究。 Product description GRL0617 is a selective and competitive noncovalent inhibitor of severe acute respiratory syndrome (SARS-CoV) papain-like protease (PLpro), with an IC50 of 0.6 μM and a Ki value of 0.49 μM. GRL0617 also inhibits SARS-CoV with an EC50 of 14.5 μM. GRL0617 can be used for the research of severe acute respiratory syndrome.
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GRL 0617
CAS number:1093070-16-6 molecular formula:C20H20N2O
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Specs
| Chinese alias | 5-氨基-2-甲基-N-[(1R)-1-(1-萘基)乙基]苯甲酰胺 | ||
| English alias | 5-Amino-2-methyl-N-(1R-naphthalen-1-yl-ethyl)-benzamide | GTPL11078 | E73459 | SQH4947NDN | 5-Amino-2-methyl-N-((1R)-1-(1-naphthalenyl)ethyl)benzamide | Cambridge id 6663564 | Q27097846 | Naphthalene and Benzamide Derivative, 25 | 1H-Indole-3-propionate | | ||
| CAS number | 1093070-16-6 | molecular formula | C20H20N2O |
| molecular weight | 304.39 g/mol | Exact mass | - |
| PSA | 55.100 Ų | logp | 4 |
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