Ledipasvir (GS-5885) acetone 是Ledipasvir的活性成分。Ledipasvir 是一种有效的丙型肝炎病毒 hepatitis C virus (HCV) NS5A 的口服抑制剂,对GT1a和GT1b复制子的EC50值分别为31 pM和4 pM。 Information Ledipasvir acetone Ledipasvir (GS-5885) acetone is the active ingredient of Ledipasvir. Ledipasvir is a potent, oral active inhibitor of the hepatitis C virus (HCV) NS5A with EC50 of 31 pM and 4 pM against GT1a and GT1b replicon, respectively. Targets GT1b replicon (Cell-free assay); GT1a replicon (Cell-free assay) 4 pM(EC50); 31 pM(EC50)
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Ledipasvir acetone
CAS number:1441674-54-9 molecular formula:C52H60F2N8O7
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| Chinese alias | - | ||
| English alias | AKOS030524068 | I11799 | Ledipasvir acetone | UNII-3J78ET35HX | EX-A1089 | Ledipasvir acetonate (JAN) | Carbamic acid, N-((1S)-1-(((6S)-6-(5-(9,9-difluoro-7-(2-((1R,3S,4S)-2-((2S)-2-((methoxycarbonyl)amino)-3-methyl-1-oxobutyl)-2-azabicyclo(2.2.1)hept-3-y | ||
| CAS number | 1441674-54-9 | molecular formula | C52H60F2N8O7 |
| molecular weight | 947.08 g/mol | Exact mass | 10mM in DMSO |
| PSA | 192.000 Ų | logp | 7.075 |
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