Mosloflavone is a flavonoid isolated from Scutellaria baicalensis Georgi with anti-EV71 activity. Mosloflavone inhibits VP2 virus replication and protein expression during the initial stage of virus infection and inhibits viral VP2 capsid protein synthesis. Mosloflavone is a promising biocide and inhibits P. aeruginosa virulence and biofilm formation. In Vitro Mosloflavone shows promising anti-inflammatory activity via inhibition of TNF-α and IL-1β with IC 50 values of 16.4 uM and 6.4 uM, respectively; inhibits TNF-α, IL-1β and iNOS levels in the supernatant of mouse macrophage cell line J774A as a dose-dependent manner, it also can be used as a starting point to discover lead structures for treatment of inflammatory and immunomodulatory diseases. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid IC50& Target:IC50: EV71,bacterial
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Mosloflavone
CAS number：740-33-0 molecular formula：C17H14O5
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| Chinese alias | 莫西林黄酮 | ||
| English alias | DTXSID00224789 | AC-34609 | BAICALEIN-6,7-DIMETHYL ETHER | SCHEMBL971985 | ESTRA-1,3,5(10)-TRIENE-3,17-DIOL, 16-(FLUORO-18F)-, (16alpha,17beta)- | SIVAITYPYQQYAP-UHFFFAOYSA-N | FT-0663427 | Mosloflavone | 4H-1-Benzopyran-4-one, 5-hydroxy-6,7-dimethoxy-2-p | ||
| CAS number | 740-33-0 | molecular formula | C17H14O5 |
| molecular weight | 298.29 g/mol | Exact mass | ≥99% |
| PSA | 65.000 Ų | logp | 3.3 |
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740-33-0 | Mosloflavon.pdf
