Peptide T is an octapeptide from the V2 region of HIV-1 gp120 . Peptide T is a ligand for the CD4 receptor and prevents binding of HIV to the CD4 receptor. In Vitro Peptide T acts to block viral entry as it inhibits in the MAGI cell assay and blocks infection in the luciferase reporter assay using HIV virions pseudotyped with ADA envelope. Peptide T selectively inhibits HIV replication using chemokine receptor CCR5 compared to CXC4. Peptide T at 10 -8 M induces IL-10 production by the human Th2 cell line and PBMC. Also peptide T at 10 -9 M concentration significantly inhibits IFN-g production by PBMC. MCE has not independently confirmed the accuracy of these methods. They are for reference only. In Vivo Peptide T is administered subcutaneously at different doses and phases of the experimental autoimmune encephalomyelitis (EAE) disease, but Peptide T neither prevents nor ameliorates EAE. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid IC50& Target:CD4, HIV
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Peptide T
CAS number：106362-32-7 molecular formula：C35H55N9O16
overview
compound introduction
Specs
| Chinese alias | - | ||
| English alias | SCHEMBL5813760 | UNII-05DYM3ZS1X | (2S,3R)-2-[[(2S)-2-[[(2S)-4-amino-2-[[(2S,3R)-2-[[(2S,3R)-2-[[(2S,3R)-2-[[(2S)-2-[[(2S)-2-aminopropanoyl]amino]-3-hydroxypropanoyl]amino]-3-hydroxybutanoyl]amino]-3-hydroxybutanoyl]amino]-3-hydroxybutanoyl]amino]-4-oxobu | ||
| CAS number | 106362-32-7 | molecular formula | C35H55N9O16 |
| molecular weight | 857.86 g/mol | Exact mass | ≥99% |
| PSA | 431.000 Ų | logp | -8.6 |
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