ALE-0540 是一种非肽小分子,是一种神经生长因子受体拮抗剂。 ALE-0540 抑制 NGF 与酪氨酸激酶 (Trk) A 或 p75 和TrkA的结合,IC50值分别为 5.88 μM、3.72 μM。 ALE-0540 可用于检查导致开发疼痛治疗药物的机制。
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Ale 0540
CAS number:234779-34-1 molecular formula:
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| Chinese alias | - | ||
| English alias | - | ||
| CAS number | 234779-34-1 | molecular formula | |
| molecular weight | 301.250 g/mol | Exact mass | ≥98% |
| PSA | 115.000 Ų | logp | 1.1 |
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