compound introduction
Hydroxyfasudil(HA1100)是Fasudil的代谢物，对ROCK1和ROCK2的IC50分别为120nM和170nM，还是血管舒张剂。 Hydroxyfasudil(HA1100), metabolite of Fasudil, is a potent Rho-kinase inhibitor and vasodilator.
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Hydroxyfasudil
CAS number：105628-72-6 molecular formula：C14H17N3O3S
overview
Specs
| Chinese alias | - | ||
| English alias | BRD-K77793136-003-02-2 | SY345499 | EYH4AU7P63 | AC-36853 | SCHEMBL123699 | Q27095449 | Hydroxyfasudil; HA-1100 | MFCD01752417 | 1(2H)-ISOQUINOLINONE, 5-((HEXAHYDRO-1H-1,4-DIAZEPIN-1-YL)SULFONYL)- | 5-(1,4-diazepan-1-ylsulfonyl)isoquinolin-1-ol | 2erz | B | ||
| CAS number | 105628-72-6 | molecular formula | C14H17N3O3S |
| molecular weight | 307.37 g/mol | Exact mass | ≥98% |
| PSA | 86.900 Ų | logp | 0.2 |
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