compound introduction
ITX3是无毒性的TrioN（N-terminal GEF domain of the multidomain Trio protein）抑制剂，IC50为76 uM，能体外抑制TrioN刺激的RhoG交换。
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ITX 3
CAS number：347323-96-0 molecular formula：C22H17N3OS
overview
Specs
| Chinese alias | (E)-2-[((2,5-二甲基-1-苯基-1H-吡咯-3-基)亚甲基]噻唑并[3,2-a]苯并咪唑-3(2H)-one | ||
| English alias | (E)-2-[(2,5-Dimethyl-1-phenyl-1H-pyrrol-3-yl)methylene]thiazolo[3,2-a]benzimidazol-3(2H)-one | 2-[(2,5-Dimethyl-1-phenyl-1H-pyrrol-3-yl)methylene]-thiazolo[3,2-a]benzimidazol-3(2H)-one | ||
| CAS number | 347323-96-0 | molecular formula | C22H17N3OS |
| molecular weight | 371.45 g/mol | Exact mass | ≥98% |
| PSA | 65.099 Ų | logp | 5.3 |
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