Bardoxolone(RTA 402)是抗氧化炎症调节剂(AIM)的先导化合物,此类AIM是转录因子Nrf2诱导剂。 Bardoxolone(RTA 402) is the lead molecule in Reata's portfolio of Antioxidant Inflammation Modulators (AIMs). The AIMs are potent inducers of the transcription factor Nrf2.
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Bardoxolone
CAS number:218600-44-3 molecular formula:C31H41NO4
overview
compound introduction
Specs
| Chinese alias | - | ||
| English alias | Bardoxolone (USAN/INN) | 2-cyano-3,12-dioxooleana-1,9(11)-dien-28-oic acid | AKOS032960362 | D09584 | BARDOXOLONE [MI] | RTA-401 | EX-A1731 | Bardoxolone | RTA 401 | J-509189 | DB12651 | RTA 402; CCDO;(4aS,6aR,6bS,8aR,12aS,14aR,14bS)-11-cyano-2,2,6a,6b,9, | ||
| CAS number | 218600-44-3 | molecular formula | C31H41NO4 |
| molecular weight | 491.66 g/mol | Exact mass | - |
| PSA | 95.200 Ų | logp | 6.4 |
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