GSK1059615是可逆的PI3Kα/β/δ/γ和mTOR双重抑制剂,IC50为0.4 nM/0.6 nM/2 nM/5 nM和12 nM。 GSK1059615 is a dual inhibitor of PI3Kα/β/δ/γ (reversible) and mTOR with IC50 of 0.4 nM/0.6 nM/2 nM/5 nM and 12 nM, respectively. A potent inhibitor of PI 3-kinase and FRAP (mTOR)
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GSK1059615
CAS number:958852-01-2 molecular formula:C18H11N3O2S
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| Chinese alias | - | ||
| English alias | Thiodiphenylamin [German] | D70652 | OXIRANE,2-[(PHENYLMETHOXY)METHYL]- | BRD-K06750613-001-01-6 | HY-12036 | NCGC00346509-02 | (Z)-5-((4-(pyridin-4-yl)quinolin-6-yl)methylene)thiazolidine-2,4-dione | GSK 1059615 sodium salt hydrate | GSK1059615 | GSK-105 | ||
| CAS number | 958852-01-2 | molecular formula | C18H11N3O2S |
| molecular weight | 333.36 g/mol | Exact mass | - |
| PSA | 97.300 Ų | logp | 3 |
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