compound introduction
ML385是一种新型的、特异的NRF2抑制剂，IC50为1.9 μM。它能抑制NRF2的下游靶基因的表达。 ML385 is a specific nuclear factor erythroid 2-related factor 2 (NRF2) inhibitor with an IC50 of 1.9 μM.
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ML385
CAS number：846557-71-9 molecular formula：C29H25N3O4S
overview
Specs
| Chinese alias | - | ||
| English alias | N-[4-[2,3-Dihydro-1-(2-methylbenzoyl)-1H-indol-5-yl]-5-methyl-2-thiazolyl]-1,3-benzodioxole-5-acetamide | 2-(Benzo[d][1,3]dioxol-5-yl)-N-(5-methyl-4-(1-(2-methylbenzoyl)indolin-5-yl)thiazol-2-yl)acetamide | ||
| CAS number | 846557-71-9 | molecular formula | C29H25N3O4S |
| molecular weight | 511.59 g/mol | Exact mass | - |
| PSA | 109.000 Ų | logp | 5.3 |
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