细胞渗透性马来酰亚胺化合物选择性抑制Werner综合征WRN解旋酶活性(IC50 = 20 µM)超过其ATP酶和核酸外切酶活性(µ50 M时分别抑制19%和 A cell-permeable maleimide compound selectively inhibits Werner syndrome WRN helicase activity (IC50 = 20 µM) over its ATPase and exonuclease activities (19% and
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MIRA-1
CAS number:72835-26-8 molecular formula:C8H9NO4
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compound introduction
Specs
| Chinese alias | 1-[(1-氧丙氧基)甲基]-1H-吡咯-2,5-二酮 | WRN 解旋酶抑制剂 | 1-((1-氧代丙氧基)甲基)-马来酰亚胺 | 1-((1-O氧代丙氧基)甲基)-1H-吡咯-2,5-二 | p53激活剂VIII | ||
| English alias | NSC 19630 | MIRA-1 | (2,5-dihydro-1H-pyrrol-1-yl)methyl propionate | BS-45665 | CCG-37541 | NCI19630 | WRN Helicase Inhibitor, NSC 19630 - CAS 72835-26-8 | 1-[(1-Oxopropoxy)methyl]-1H-pyrrole 2,5-dione | N-(Propionyloxymethyl)maleimide; NSC 19630 | (2,5-d | ||
| CAS number | 72835-26-8 | molecular formula | C8H9NO4 |
| molecular weight | 183.16 g/mol | Exact mass | ≥99% |
| PSA | 63.700 Ų | logp | -0.1 |
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