Caspase-8抑制剂II是有效的，细胞可渗透的，不可逆的caspase-8和颗粒酶B抑制剂。该化合物还抑制HeLa细胞中流感病毒诱导的凋亡。半胱天冬酶抑制剂在研究生物学过程中起着重要作用，而半胱天冬酶家族的蛋白质是凋亡机制的关键调节剂，可破坏对细胞存活至关重要的特定靶蛋白。然后可以使用半胱天冬酶标准的凋亡测定法来检查处理过的细胞是否有凋亡证据。|对于荧光定量的半胱天冬酶6活性测定，可从圣克鲁斯获得以下半胱天冬酶凋亡检测试剂盒：Caspase-8 Kit。 Caspase-8 inhibitor II is a potent, cell-permeable, irreversible inhibitor of caspase-8 and granzyme B. This compound also inhibits influenza virus-induced apoptosis in HeLa cells. Caspase inhibitors play an important role in investigating biological processes and the caspase family of proteins function as key regulators of apoptotic machinery, acting to destroy specific target proteins that are critical to cell survival. Caspase-standard apoptosis assays can then be used to examine treated cells for evidence of apoptosis.|For the fluorometric determination of caspase-6 activity, the following caspase apoptosis detection kit is available from Santa Cruz: Caspase-8 Kit .
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Caspase-8抑制剂II
CAS number：unknown molecular formula：
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| Chinese alias | - | ||
| English alias | Z-Ile-Glu(O-ME)-Thr-Asp(O-Me) fluoromethyl ketone | Z-IETD-FMK | ||
| CAS number | unknown | molecular formula | |
| molecular weight | - | Exact mass | ≥98% |
| PSA | - | logp | - |
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