(±)12-HETE是通过花生四烯酸的非酶氧化产生的六种单羟基脂肪酸之一。(±)12-HETE的生物活性与其组成对映体相似。它聚集中性粒细胞,EC50值为40 nM。 (±)12-HETE is one of the six monohydroxy fatty acids produced by the non-enzymatic oxidation of arachidonic acid. The biological activity of (±)12-HETE is similar to that of its constituent enantiomers. It aggregates neutrophils with an EC50 value of 40 nM.
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(±)12-HETE
CAS number:71030-37-0 molecular formula:C20H32O3
overview
compound introduction
Specs
| Chinese alias | - | ||
| English alias | 12-Hete | 5,8,10,14-Eicosatetraenoicacid, 12-hydroxy-, (5Z,8Z,10E,14Z)- | CHEBI:84447 | (5Z,8Z,10E,14Z)-12-hydroxyicosatetraenoic acid | 12-Hete, (+/-)- | LMFA03060088 | SR-01000946924 | Q6F9H3VPC0 | SCHEMBL7718635 | 5,8,10,14-Eicosatetraenoicacid,12-hydr | ||
| CAS number | 71030-37-0 | molecular formula | C20H32O3 |
| molecular weight | 320.47 g/mol | Exact mass | ≥95% |
| PSA | 57.500 Ų | logp | 5.2 |
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