CAS number：2095719-92-7 molecular formula：C29H31ClFN5O5
Information ASTX-029 ASTX-029 is an orally bioavailable inhibitor of the extracellular signal-regulated kinases (ERK) 1 and 2 , with potential antineoplastic activity. ASTX-029 inhibits ERK-dependent tumor cell proliferation and survival. Targets ERK1 ; ERK2
| Chinese alias | - | ||
| English alias | BDBM418007 | AKOS040759413 | (2~{R})-2-[5-[5-chloranyl-2-(oxan-4-ylamino)pyrimidin-4-yl]-3-oxidanylidene-1~{H}-isoindol-2-yl]-~{N}-[(1~{S})-1-(3-fluoranyl-5-methoxy-phenyl)-2-oxidanyl-ethyl]propanamide | compound 15 [PMID: 34387469] | EX-A4375 | ERK1/2 in | ||
| CAS number | 2095719-92-7 | molecular formula | C29H31ClFN5O5 |
| molecular weight | 584.04 g/mol | Exact mass | - |
| PSA | 126.000 Ų | logp | 2.9 |
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