CAS number：20137-37-5 molecular formula：C3OH48O5
Rotundic acid 是一种从圆形肠球菌 (I. rotunda) 中获得的三萜类化合物，可通过 AKT/mTOR 和 MAPK 途径在肝细胞癌中诱导 DNA 损伤和细胞凋亡。Rotundic acid 具有抗炎和保护心脏的能力。 Information Rotundic acid Rotundic acid (Rutundic acid), a natural compound, exhibit cytotoxic activities toward human hepatocellular carcinoma (HepG2), malignant melanoma (A375), SCLC (NCI-H446), breast cancer (MCF-7), and colon cancer (HT-29) cell lines.RA induces cell cycle arrest, DNA damage, and apoptosis by modulating the AKT/mTOR and MAPK pathways .
| Chinese alias | - | ||
| English alias | MFCD13186912 | I1exo1ic acid | (1R,2R,4aS,6aR,6aS,6bR,8aR,9R,10S,12aR,14bS)-1,10-dihydroxy-9-(hydroxymethyl)-1,2,6a,6b,9,12a-hexamethyl-2,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carboxylic acid | Rotundic acid | (1R,2R,4aS,6aS,6bR,8aR,9R | ||
| CAS number | 20137-37-5 | molecular formula | C3OH48O5 |
| molecular weight | 488.7 g/mol | Exact mass | ≥98% |
| PSA | 98.000 Ų | logp | 4.253 |
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