compound introduction
EI1是EZH2选择性抑制剂，对野生型EZH2和EZH2 Y641F突变型的IC50分别为15 nM和13 nM。 EI1 is a potent and selective EZH2 inhibitor with IC50 of 15 nM and 13 nM for EZH2 (WT) and EZH2 (Y641F), respectively.
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EI1
CAS number：1418308-27-6 molecular formula：C23H26N4O2
overview
Specs
| Chinese alias | - | ||
| English alias | 6-cyano-N-[(4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl]-1-(pentan-3-yl)-1H-indole-4-carboxamide | NCGC00351776-03 | HY-15573 | AS-55788 | CCG-268533 | EI1; Ezh2 inhibitor | 6-Cyano-N-((4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-1-(pentan-3- | ||
| CAS number | 1418308-27-6 | molecular formula | C23H26N4O2 |
| molecular weight | 390.48 g/mol | Exact mass | - |
| PSA | 86.900 Ų | logp | 3.400 |
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