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SCR130

CAS number:2377858-38-1    molecular formula:C19H13Cl2N3O2S

overview

compound introduction

SCR130 是一种基于 SCR7 的 DNA 非同源末端连接 (NHEJ) 抑制剂。SCR130 以依赖连接酶 IV 的方式抑制 DNA 的末端连接。SCR130 对连接酶 IV 具有特异性,对连接酶 III 和连接酶 I 介导的连接的影响很小或没有影响。SCR130 诱导细胞凋亡 (apoptosis),并具有抗癌活性。

Specs

Chinese alias-
English alias1,7,9-Triazaspiro[4.5]dec-1-ene-6,10-dione, 2,4-bis(4-chlorophenyl)-8-thioxo
CAS number2377858-38-1molecular formulaC19H13Cl2N3O2S
molecular weight418.30 g/molExact mass≥98%
PSA-logp-

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