CAS number：1201673-28-0 molecular formula：C21H28N6O
BPKDi 是一种有效的联吡啶 PKD 抑制剂，对 PKD1、PKD2 和 PKD3 的 IC50 分别为 1 nM、9 nM 和 1 nM。BPKDi 阻断心肌细胞中 IIa 类 HDAC 的信号依赖性磷酸化和核输出 BPKDi is a potent bipyridyl PKD inhibitor with IC50s of 1 nM, 9 nM and 1 nM for PKD1, PKD2 and PKD3, respectively. BPKDi blocks signal-dependent phosphorylation and nuclear export of class IIa HDACs in cardiomyocytes
| Chinese alias | - | ||
| English alias | 2-[2-(cyclohexylamino)pyridin-4-yl]-6-piperazin-1-ylpyridine-4-carboxamide | 2′-(cyclohexylamino)-6-(1-piperazinyl)-[2,4′-bipyridine]-4-carboxamide | ||
| CAS number | 1201673-28-0 | molecular formula | C21H28N6O |
| molecular weight | 380.49 g/mol | Exact mass | - |
| PSA | 96.200 Ų | logp | 2.2 |
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