CRT0066101 是一种有效的 PKD 抑制剂,对 PKD1、PKD2 和 PKD3 的 IC50 值分别为 1 nM、2.5 nM 和 2 nM。CRT0066101 也是一种有效的 PIM2 抑制剂,IC50 约为 135.7nM。CRT0066101 具有抗癌作用。 CRT0066101 is a potent and active PKD inhibitor with IC50 values of 1 nM, 2.5 nM and 2 nM for PKD1, PKD2, and PKD3, respectively. CRT0066101 is also a potent PIM2 inhibitor with an IC50 of ~135.7 nM. CRT0066101 has anticancer effects
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CRT 0066101
CAS number:956123-34-5 molecular formula:C18H22N6O
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| Chinese alias | - | ||
| English alias | (R)-2-(4-((2-Aminobutyl)amino)pyrimidin-2-yl)-4-(1-methyl-1H-pyrazol-4-yl)phenol | 2-[4-[[(2R)-2-Aminobutyl]amino]pyrimidin-2-yl]-4-(1-methylpyrazol-4-yl)phenol | 2-[4-[[(2R)-2-Aminobutyl]amino]pyrimidin-2-yl]-4-(1-methyl-1H-pyrazol-4-yl)phenol dihydrochl | ||
| CAS number | 956123-34-5 | molecular formula | C18H22N6O |
| molecular weight | 338.41 g/mol | Exact mass | - |
| PSA | 102.000 Ų | logp | 1.8 |
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