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CRT 0066101

CAS number:956123-34-5    molecular formula:C18H22N6O

overview

compound introduction

CRT0066101 是一种有效的 PKD 抑制剂,对 PKD1、PKD2 和 PKD3 的 IC50 值分别为 1 nM、2.5 nM 和 2 nM。CRT0066101 也是一种有效的 PIM2 抑制剂,IC50 约为 135.7nM。CRT0066101 具有抗癌作用。 CRT0066101 is a potent and active PKD inhibitor with IC50 values of 1 nM, 2.5 nM and 2 nM for PKD1, PKD2, and PKD3, respectively. CRT0066101 is also a potent PIM2 inhibitor with an IC50 of ~135.7 nM. CRT0066101 has anticancer effects

Specs

Chinese alias-
English alias(R)-2-(4-((2-Aminobutyl)amino)pyrimidin-2-yl)-4-(1-methyl-1H-pyrazol-4-yl)phenol | 2-[4-[[(2R)-2-Aminobutyl]amino]pyrimidin-2-yl]-4-(1-methylpyrazol-4-yl)phenol | 2-[4-[[(2R)-2-Aminobutyl]amino]pyrimidin-2-yl]-4-(1-methyl-1H-pyrazol-4-yl)phenol dihydrochl
CAS number956123-34-5molecular formulaC18H22N6O
molecular weight338.41 g/molExact mass-
PSA102.000 Ųlogp1.8

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