n-Butyl-β-D-fructofuranoside

n-Butyl-β-D-fructofuranoside could be isolated from kangaisan. n-Butyl-β-D-fructofuranoside induces apoptosis through the mitochondrial pathway. n-Butyl-β-D-fructofuranoside can be used for cancer research In Vitro n-Butyl-β-D-fructofuranoside (0-23.6 μg/mL; 24-78 hours) has antiproliferation activity and inhibits the viability of Bel-7402 cells. n-Butyl-β-D-fructofuranoside (0-75 μg/mL; 0-72 hours) inhibits BEL-7402 cells by interfering with cell cycle and inducing apoptosis. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Cell Viability AssayCell Line: Bel-7402 cells Concentration: 0.47, 2.95, 5.90, 11.8, 17.7 and 23.6 μg/mL Incubation Time: 24, 48 and 72 hours Result: Inhibited the proliferation of Bel-7402 cells at both time- and dose-dependent manner. Cell Cycle AnalysisCell Line: Bel-7402 cells Concentration: 0, 50 and 75 μg/mL Incubation Time: 24, 48 and 72 hours Result: Induced cell cycle arrest at G0/G1 phase. Western Blot AnalysisCell Line: Bel-7402 cells Concentration: 23.6 μg/mL Incubation Time: 0, 24, 48 and 72 hours Result: Decreased Bcl-2 and increased Bax and p53 levels in a time manner. Form:Oil IC50& Target:Bax Bcl-2

No numbering system information yet

No physical and chemical property information yet

No safety information yet

No production method and use information yet

No upstream information yet

No downstream information yet

No related product information yet