Toddaculin is a natural coumarin that can induce differentiation and apoptosis in leukemic cells. Toddaculin suppresses excess osteoclast activity and enhances osteoblast differentiation and mineralization. Toddaculin also exhibits anti-inflammatory activity . In Vitro Toddaculin (5-250 μM; 24-72 h) shows anti-proliferative activity in U-937 cells, with an IC 50 of 51.38 μM. Toddaculin (25-250 μM; 24-48 h) induces partial differentiation in U-937 leukemic cells. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid
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Toddaculin
CAS number:4335-12-0 molecular formula:C16H18O4
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| Chinese alias | 托达克林 | ||
| English alias | starbld0003785 | 5,7-Dimethoxy-6-(3-methylbut-2-en-1-yl)-2H-chromen-2-one | SCHEMBL15941538 | E80586 | 5,7-dimethoxy-6-(3-methylbut-2-enyl)chromen-2-one | AKOS040763013 | HY-N9359 | Toddaculine | MS-23895 | 2H-1-Benzopyran-2-one, 5,7-dimethoxy-6-(3-methyl | ||
| CAS number | 4335-12-0 | molecular formula | C16H18O4 |
| molecular weight | 274.31 g/mol | Exact mass | ≥99% |
| PSA | 44.800 Ų | logp | 3.8 |
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