MSN-50 is a Bax and Bak oligomerization inhibitor. MSN-50 efficiently inhibits liposome permeabilization, prevents genotoxic cell death and promotes neuroprotection In Vitro MSN-50 (0~10 uM) inhibits dye release from liposomes in a concentration-dependent fashion. MSN-50 (0~40 uM) inhibits tBid/Bax-mediated MOMP (mitochondrial outer membrane permeabilization) in a concentration-dependent manner and shows concentration-dependent inhibition of Bak-mediated MOMP. MSN-50 inhibits both Bax and Bak after activation by either cBid or Bim. MSN-50 (5 μM; BMK cells) inhibits apoptosis induced by actinomycin D and staurosporin (STS) . MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid IC50& Target:Bax Bak
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MSN-50
CAS number：1592908-75-2 molecular formula：C36H38BrN3O6
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| Chinese alias | - | ||
| English alias | - | ||
| CAS number | 1592908-75-2 | molecular formula | C36H38BrN3O6 |
| molecular weight | 688.619 g/mol | Exact mass | ≥98% |
| PSA | - | logp | - |
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