Lusianthridin, a pure compound from Dendrobium venustum , have an anti-migratory effect. Lusianthridin enhances c-Myc degradation through the inhibition of Src-STAT3 signaling. In Vitro Lusianthridin (0-100 μM) inhibits cell viability at concentrations greater than 50 μM in both H460 and H292 cells. Lusianthridin significantly reduces the CSC populations in both H460 and H292 cells of the CSC spheres, with a significant decrease in the size of the H460 CSC spheres by approximately 10%, 63%, and 77% at day 3 at concentration 5, 10, and 20 μM Lusianthridin, respectively. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Cell Viability AssayCell Line: The human non-small cell lung cancer cell lines, NCI-H460, and NCI-H292 cells. 0-100 μM. Concentration: 0-100 μM. Incubation Time: 24 h. Result: Caused a significant reduction in terms of cell viability at concentrations greater than 50 μM in both H460 and H292 cells. Form:Solid
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Lusianthridin
CAS number：87530-30-1 molecular formula：C15H14O3
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| Chinese alias | 卢西恩紫丁香 | ||
| English alias | DTXSID50331917 | BDBM246496 | 2,5-Dihydroxy-7-methoxy-9,10-dihydrophenanthrene (14) | CHEBI:28678 | FS-7984 | 4,7-Dihydroxy-2-methoxy-9,10-dihydrophenanthrene | SCHEMBL4743850 | 7-methoxy-9,10-dihydrophenanthrene-2,5-diol | Q27103833 | HY-121418 | Lusiant | ||
| CAS number | 87530-30-1 | molecular formula | C15H14O3 |
| molecular weight | 242.27 g/mol | Exact mass | ≥98% |
| PSA | 49.700 Ų | logp | 3.1 |
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