compound introduction
IRF1-IN-1 (Compound I-2) 是一种IRF1抑制剂。IRF1-IN-1 可减少 IRF1 对 CASP1 启动子的招募。IRF1-IN-1 抑制细胞死亡信号通路 (即抑制Caspase 1、GSDMD、IL-1和PARP1的裂解)。IRF1-IN-1 对电离辐射引起的皮肤炎症性损伤有保护作用。
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3-(4-oxo-3(4H)-quinazolinyl)-N-[4-(1-piperidinylsulfonyl)phenyl]propanamide
CAS number：701225-07-2 molecular formula：C22H24N4O4S
overview
Specs
| Chinese alias | - | ||
| English alias | - | ||
| CAS number | 701225-07-2 | molecular formula | C22H24N4O4S |
| molecular weight | 440.5 g/mol | Exact mass | ≥99% |
| PSA | 108.000 Ų | logp | 1.7 |
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